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Cisterna Biologics
High-quality mRNA for therapeutic application
Cisterna
Biologics
Cisterna uses advanced technologies to build the next generation of mRNA.
Our Mission
Cisterna is dedicated to advancing the field of mRNA-based therapeutics by providing exceptionally high-quality mRNA. Our broader mission is to tackle the multifaceted challenges inherent in production of mRNA for R&D. These include quality, quantity, cost and delivery lead time. As mRNA technology continues to evolve, we are committed to providing rapid, innovative and effective solutions to unlock the boundless potential of mRNA as a therapeutic modality.
Benefits of HPLC-purified mRNA without HPLC purification
Why does mRNA purity matter?
With the success of mRNA-based Covid vaccines, there is now great momentum to develop mRNA-based therapeutics to cure previously incurable diseases. One major hurdle in successfully deploying mRNA therapy is the difficulty in obtaining mRNA without product-related impurities - double stranded RNA (dsRNA), long RNA impurities (LRNA) and short truncated RNA (stRNA). Current production methods, without additional purification steps to remove these impurities, can result in mRNA with increased immunogenicity and decreased therapeutic efficacy.
Demanding applications require a demanding technology
Cisterna's technology can eliminate
product-related impurities
Reliability ensured through consistently homogeneous mRNA.
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